Autism correlated with guthealth. More evidence links gut bacteria to developmental disorders.
There is mounting evidence of a relationship between the microbiome and autism. Taken in isolation one study that challenges conventional thinking about any condition such as autism should be treated with suspicion. However, increasing scientific research into gut health and wellbeing is starting to shift the thinking about human health in a completely new direction.
A number of studies have observed abnormal gut microbiota correlated with a range of conditions including autism. However the issue of causality is still uncertain. So what does this mean? In short that the bacteria in the human gut demonstrates a different profile in people with autism than people without autism. The scientific term for a balance and blend of gut bacteria that falls outside of the ‘normal’ range is known as dysbiosis. Exactly how gut dysbiosis is linked to autism is still far from clear. There is the possibility that dysbiosis is the effect of a condition rather than the cause of it, although we know there is a two-way relationship between the gut and the brain through the gut-brain access.
A recent overview of research into gut microbiota and dysbiosis in autism found that gut microbiota probably has a mediating role in ASD. By logical deduction, we can be confident that diet at some level is likely to be connected to the development of ASD or the maintenance of its symptoms.
So while we are waiting for science to deliver ‘conclusive’ findings that will help us understand more about autism, what shall we do?
Clearly, we should attempt to establish a healthy gut. The list of health problems linked to dysbiosis grows almost every day, they currently include a range of cancers, heart disease and even dementia! Amongst the simple measures every person can engage with immediately to keep a healthy gut, are to avoid processed meats and eat more fermented foods.
It’s far too early to draw firm conclusions about diet and complex developmental conditions such as ASD. But a picture is starting to emerge were just as diet influences gut health, gut health influences physical and mental wellbeing, there was never a greater case for embracing the maxim ‘we are what we eat’.
Milk and water kefir, resources for anyone thinking of making their own at home.
Kefir resources to help you on the journey of fermentation
Why not make your own kefir, it’s good for you, cost effective and much simpler than you’d imagine. Kefir is really hot right now, it’s got a high visibility in the health and fermented food niche and shows signs that it could break out in the mainstream. I say this as a guy that never heard of kefir a few years ago, now I’m making my own at home. Although making kefir is pretty easy there are a few potential pitfalls, particularly to people new to fermentation, so I decided to share resources that I found useful.
For our own practical guide into home kefir production click here.
Keeping your kefir going, a practical video guide on how to keep the grains living whilst harvesting the product.
There is a BBC guide to the health benefits of kefir, it’s a little bit dated in approach, I guess you wouldn’t expect anything less from the BEEB.
Mad Millie Kefir Kit at Lakeland was our first experience of DIY kefir. The kit contains everything you need to get started and so is a useful first step for beginners. The Lakeland site also has a lot of items that fermenters might find useful including, Kilner jars, cheesecloth, wooden utensils.
A journal study exploring the microbial interactions in kefir, largely linked to the composition and health benefits of lactobacillus.
The Wikepedia kefir page is not the best DIY resource on the internet but it gives a good overview and links to a lot of the relevant research to anyone interested in the science.
The Cultures for Health guide to Kefir, useful information for new and experienced fermenters. Links to plenty of related articles including some water kefir insights.
For information on vegan kefir, visit the Nourished Kitchen website. All the ins and outs of home productions, tips and recipes.
What is fermentation and how is it related to health and well being?
The growing area of study linking human microbiota to health and wellbeing is seeing the development of new learning opportunities. The extent to which microorganisms on our skin and in our bodies meditate our lived experience can be understood through a free Coursera module, Gut check; exploring your microbiome. Maggie and I have completed the first two weeks, I thought potential future students might be interested in hearing more about what this course entails.
This MOOC is produced by the University of Colorado Boulder and the tutors are all linked to the institution; Professor Rob Knight, Dr. Jessica L. Metcalf and Dr. Katherine R. Amato.
As you might expect week one offers an overview of the subject area. Explanations are given for what microbes are in relation to each other (Bacteria, Archaea, Eukaryotes and Viruses) and all living organisms. The role of microbes more generally is explained before looking at how microbes and humans interact. Definitions include the distinction between human microbiota (a community of microbes), and the microbiota (the total genes in the microbiota).
The material highlights a number of interesting microbiome facts including that whilst humans share 99.99% of the same DNA, two humans may only have 10% of their microbiomes in common. This is one of the reasons why gut bacteria is thought to be influential in how we experience life. Although the majority of our microbes live in our gut, there are communities all over us (mouth, skin, vagina). We are born sterile and then communities of microbiota become established at a very early age, changes to these communities happen throughout our lives. The module material clearly illustrates that the microbes we are exposed to have an import role in our lives.
The first week provides a useful introduction to the subject and offers a context for later material. Beyond week 1, the course follows a much stronger academic path. Explaining the science behind the study of microbiota and moving onto subjects such as alpha diversity and ‘fuzzy microbes’. If you’ve tried the MOOC what do you think?
Kefir appears to offer significantly greater benefit than commercially produced probiotic drinks.
Dr Michael Mosley has been helping to run a study for the BBC looking at the relative benefits to gut health from a range of products. Volunteers and scientists collaborated to try to discover which of three probiotics/prebiotics had the biggest positive impact on gut bacteria.
The first product was a commercially available drink, branded as a probiotic and available in major supermarkets. The second item up for comparison was kefir, a traditional milk and yeast fermented substance, a little like yogurt. These first two foods were compared with vegetables high in natural prebiotic fibre called inulin. Inulin is found in range of foods including chicory (chicory root is a rich source) and scallions (onions, leeks and garlic).
The poorest preforming of the three in this trial was the probiotic drink. The participants in this group demonstrated a modest (statistically non significant) change in lachnospiraceae gut bacteria. Conversely significant changes in gut flora were seen in the group consuming prebiotic fibre. The people that consumer kefir enjoyed the most positive increase to gut bacteria.
It should be pointed out that any comparison between prebiotics and probiotics is not a like for like test. Prebiotics deliver the food that supports existing bacteria and create the conditions for further colonization. A probiotic is intended to introduce microorganisms directly into the body.
The BBC study concluded that traditionally produced fermented foods (or even home made versions) may offer the greatest benefits to consumers in terms of increased gut flora. A key problem with mass produced fermented foods and drinks is pasteurisation. Pasturised goods are regarded as safer, which also correlates to a longer shelf life. By comparison traditionally made kefir has to be consumed in a relatively short space of time. This is perhaps the choice we consumers face, if we want maximum health benefits from the food we make or buy we may have to sacrifice some of the convenience of long sell by dates.
Home fermentation, have you tried the Kilner fermentation set?
Is a home fermentation kit necessary? For the occasional production of sauerkraut I’m not sure that special equipment is essential. Maggie has managed to keep us supplied with our fermented foods simply by using medium sized jam jars, and a range of normal kitchen utensils. The point she always stresses is that everything has to be clean. The fermentation vessel should be thought of as a bacterial incubator. If you incorporate harmful bacteria into the incubator it will inevitably grow quickly. You should throw any tainted product away , clean everything and start again. One of the many appealing aspects of home fermentation is the relatively low cost of fermenting produce. Consider that at current prices a liter of organic sauerkraut can be created for less than 50p (ten bob!).
I know that previous generation of home fermenters from Poland and Germany actually had a range of fermentation pots and tools that were accumulated through the course of married life (I don’t remember seeing any of these is the kitchen of my mother or grandmother). In particular ceramic pots that were dedicated fermentation vessels. They had necks wide enough that a small plate or large saucer could be accommodated within to keep the fermented product under the water level.
With the rising interest in home fermentation equipment has passed from specialist shops and online retailers into mainstream retail outlets. We purchased a Kilner fermentation kit at the weekend. Our primary motivation was to increase the volumes of our product. Not only has our own consumption increased but we are also sharing more with our own friends and family. It certainly seems that the public awareness of the benefits of fermentation is growing. The Kilner kit was fairly priced (£18) when compared to similar products and the fermenting jar was around the size we were looking for (3 liters). It all seems OK, we’ll report back when our first batch is ready (cabbage and carrot). We have no particular connection with Kilner, save that we use their 1liter fermentation jars already.
We’d be really interest in what other home fermenters use, and any equipment related tips would be most welcome. Feel free to leave any suggestions, comments or feedback in the box below.
Is temperature linked to the quality of your sauerkraut?
In the short time we have been running this blog we have been asked about the optimum temperature for the fermentation process to take place. We have successfully fermented a range of foodstuffs at room temperature, let’s say from 18oC to 22o. There is no method in this, it is simply that Maggie was brought up to leave the fermenting vegetables in the kitchen or a heated utility room. As such we’ve never been tempted to leave them in the garage or garden shed. As different types of cabbage take different amounts of time to ferment into sauerkraut, it always seemed likely that temperature is a variable in the process.
I eventually became impatient not knowing, I was also intrigued by the idea that the quality of our own sauerkraut fermentation could be qualitatively improved by allowing it to take place at a slightly lower or higher temperature. The first two science papers I found dealing with the issue didn’t offer explicit conclusions, however third time lucky! India is one of the world’s big producers of cabbage, the spoiling of the raw cabbage before it gets to the consumer is a significant problem. So Indian interest in fermentation is something that is culturally relevant but also has commercial implications. An article in the Indian Journal of Ecology from 2017, Effect of Temperature on Fermentation and Quality of Sauerkraut provided a lot of useful data.
In an experiment, Pran Krishna Thakur, Payel Panja and Jahangir Kabir tested the quality of sauerkraut produced at a low (15o-20o C), ambient (25o-30o C) and high (35o-40o C) temperatures. The paper is well written if you’d like to know more about yeast and bacterial profiles of sauerkraut fermentation at different temperatures follow the link. However the headline is that the sauerkraut was of a higher quality when fermented at the lower temperature (15o-20o C). This is in line with the general advice, however it’s worth noting that the experiment was undertaken with the shaan variety. I suspect that there may be some variability with different types of cabbage, but that’s a story for another day.